BIOL4352 | Protein Structure

Take home final (part2) - Deadline is 12pm Monday the 7th of December.

Answer the following questions A,B,C. For each question use the format given below:

1.   Your answer should be one or two pages long (font size 12, single- spaced).

2.   Include three recent (no older than 2015) primary research articles in your answer and cite them within your answer and in reference list. *

3.   Include diagrams of protein structures (don t forget to cite them). Note that picture or diagram space must be excluded for estimating text length.

4.   Include your name in the upper right corner.

5.   Name your file by your Last name and first initial.

6.   Send me an e-copy no later than noon on Monday the 7th of December.

7.   Bring the hard copy to your final exam if your class is Face-to-face style.

Questions:

A.  Aminoacyl-tRNA synthetases (ARSs) are specific to each tRNA. Select one ARS** and review what is currently known about its structure, specificity, function and detailed enzymatic mechanism. Also, could it be used as a target molecule for any unwanted cells (cancer, pathogenic bacteria etc.) Does such a treatment exist?


B. Transcription factors are very important in gene regulation processes. Select one such a factor and review what is currently known about its involvement in any diseases.

C.  Explain the principal behind an mRNA vaccines, its advantages and disadvantages.

* Citation Format: AuthorLastName, AuthorInitials. (Year). "ArticlTitle." Journal Title, Volume Number

(Issue Number): pages.

https://guides.lib.uw.edu/c.php?g=341448&p=2809205

**or you will be assigned to a certain type of ARS