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42. explain the mode of action of enzymes
2.1 described the structure of enzymes and explained how their structure is linked to their function
2.2 explained the concept of activation energy
2.3 compared the lock and key and induced fit models of enzyme action
2.4 explain the effect of three external factors on enzyme activity
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Assignment title: Biological Molecules: Structure and Function of Enzymes
Assignment brief Task 1: The lock and key and induced fit models have been used to describe the mode of action of enzymes. Compare the two models. You need to consider the follow: The structure of enzymes and how this is linked to their function. How enzymes affect activation energy You may use hand drawn diagrams to help you complete this task. (AC 2.1, 2.2 & 2.3) Task 2: Amylase is an enzyme that is found in saliva, it catalyses the hydrolysis of starch into glucose. Two experiments were carried out to investigate the factors affecting enzyme activity. Experiment 1 investigated the breakdown of starch by amylase at different pHs and Experiment 2 investigated the breakdown of starch by amylase at different temperatures. The resulted are shown in the tables below. For each experiment: Calculate the rate of reaction Produce a graph Write a conclusion explaining the results. Table 1. Effect of pH on Amylase pHTime for starch to disappear (s)Rate of Reaction (1/t) 5 120 6 40 7 30 8 50 9 150 Table 2. Effect of Temperature on Amylase TemperatureTime for starch to disappear (s)Rate of Reaction (1/t) 25 549 30 276 35 174 40 200 45 462 (AC 2.4) Task 3: The graph below shows the affect of a competitive and non-competitive inhibitor on the rate of reaction. Using the graph: Identify the line that represents the affect of the competitive and non-competitor inhibitor on the rate of reaction Explain why the rate of reaction is affected in this way for each type of inhibitor (AC 2.4) Word count is 1000 words (+/- 10%). Word count must be added at the end of each Task. You should include a Bibliography and a reference list, both presented using Harvard style of referencing. The quality of English (grammar, spelling and punctuation) and bibliography will be considered. The assignment must be submitted onto Turnitin, including any diagrams.
Assignment Rules and Procedures: The assignment must contain appropriate citations and references. Failure to submit either will result in a resubmission. The assignment will be capped at a Pass if the word count is breached. The assignment must have an acceptable originality report; a significant breach will be considered as a failure to submit your assignment on time. The assignment must be submitted through Turnitin. Deadline dates and times can be seen on TurnitinIf there is an external problem with the Turnitin site, submit your completed assignment via e-mail to register the date and time, then submit to Turnitin as soon as the problem has been rectified. Your work will not be marked until it is submitted through Turnitin. No changes are permitted to the original after the deadline.If Turnitin has highlighted the submission in red the assignment is late and will be capped at a pass unless an extension has been agreed. Extensions need to follow CAVA guidelines and are awarded by the Access Panel, not the subject tutor. This is subject to external validation by CAVA
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